Yuri Iozzo

Company: ModeX Therapeutics

Job title: Associate Director - Digital Biology

Bio:

Yuri Iozzo, PhD eqv (AKA Egor Svidritskiy) is a structural biologist and machine learning expert whose early research, while at UMass Medical School, on translation termination uncovered foundational insights into ribosome dynamics. He has been at the forefront of advancing cryo-electron microscopy techniques, including the development of Ensemble cryo-EM. He led the charge in applying cryo-EM innovations to biologics drug discovery at Sanofi. As Head of the Digital Biology group at ModeX Therapeutics, Yuri drives the integration of machine learning to de-risk and accelerate therapeutic R&D, combining structural biology and AI to enable next-generation discovery pipelines.

Seminars:

Cytokine-Based Machine Learning Approach to Predict Protein Immunogenicity 3:00 pm

Explore cytokine-based machine learning as a novel framework for modeling T-cell activation beyond MHC binding predictions Demonstrate how the data-anchored model can improve immunogenicity prediction and enhance immune response modeling Discuss emerging applications of cytokine-informed models and their potential as complementary tools in therapeutic design and immunological researchRead more

day: Conference Day Two