Randolph Lopez

Company: A-Alpha Bio Inc.

Job title: Co-founder & Chief Technology Officer

Seminars:

Affinity-Aware In Silico Humanization Using a Domain-Specific Deep Learning Affinity Oracle 3:45 pm

Developed and validated an affinity oracle for antibody-antigen binding by integrating context-specific protein-protein interaction (PPI) data with ESM-2 and transfer learning techniques Leveraged the affinity oracle to assess mutations that revert antibodies to their germline state for the purpose of humanization Conducted experimental validation of model predictions through biophysical characterizationRead more

day: Day One