David Danciu

Company: Cradle Bio

Job title: Chief Technology Officer

Seminars:

From Enzymes to Antibodies – the Surprising Insights of ML-driven Optimization 11:30 am

In this presentation, we will discuss unexpected findings from our work on ML-guided, lab-in-the-loop protein design targeting affinity, expression, and stability for antibodies. Notably, we demonstrate that it is possible to achieve improved binding affinity without altering the complementarity-determining regions (CDRs). On the other hand, we show that even substantial modifications to CDRs, including the…Read more

day: Day One