Christopher Negron
Company: AbbVie
Job title: Senior Scientist
Seminars:
Improving the Drug-Like Properties of Affinity-Matured Antibodies via QSPR 3:00 pm
Affinity maturation often produces a panel of prospective lead candidates These candidates have a diverse range of drug-like properties Utilizing QSPR and machine Learning we are able to identify residues that drive an unwanted drug-like property In this talk, we validate this approach by mitigating off-target interactions of high-affinity bindersRead more
day: Day Two