Christopher Negron

Christopher Negron

Company: AbbVie

Job title: Senior Scientist


Improving the Drug-Like Properties of Affinity-Matured Antibodies via QSPR 1:00 pm

Affinity maturation often produces a panel of prospective lead candidates These candidates have a diverse range of drug-like properties Utilizing QSPR and machine Learning we are able to identify residues that drive an unwanted drug-like property In this talk, we validate this approach by mitigating off-target interactions of high-affinity bindersRead more

day: Day Two

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