Identification of VHH-binders From an Immunized-Antibody Repertoire Using Computational Methods
Time: 11:30 am
day: Conference Day Two
Details:
- Improved early antibody selection with structure-informed screening
- In silico strategy yielded a 50-60% hit rate in identifying antigen-specific binders in two different cases
- High-affinity inhibitors can be found without experimental screening
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