13-15 November 2018

Woburn, Boston, MA

Day One
Wednesday 14th November 2018

Day Two
Thursday 15th November 2018

07.55
Chair’s Opening Remarks

Challenges and Opportunities in Computationally Engineering Biopharmaceuticals

08.00
Prediction of the Methionine Oxidation and Degradation Propensity in Monoclonal Antibodies

08.30
Standardization & Quality Considerations for Machine Learning from Physical Protein Samples

  • Jeremy Shaver Principal Scientist, Data Science, Just Biotherapeutics

09.00
Break out Round Table Discussions: How Should We Move Towards a Compendial Approach to Predictive Modelling?

10.30
Moderator’s Feedback Panel

10.45
Morning Refreshments & Networking

Stability & Interface Engineering of Complex Biologics

11.15
Structure Guided Approaches to the Azymetric Bispecific Platform Design

  • Antonios Samiotakis Principal Scientist, Technology Integration & Bioinformatics, Zymeworks Inc

11.45
Platformization of Multi-Specific Protein Engineering: From Handling Complex Data to In-Silico Design & High-Throughput Screening

  • Norbert Furtmann Norbert Furtmann, Lab Head Bioinformatics, High Throughput Biologics, R&D Biologics Research/Protein Therapeutics, , Sanofi-Aventis

12.15
Lunch & Networking

Approaches to Explore Biocatalysis & Enzyme Design

13.15
Computational Enzyme Design: From Small-Molecule Manufacturing to New Biologics

13.45
Coupling Computational Tools with High Throughput Screening & Deep Sequencing to Guide Enzyme Design

14.15
Afternoon Refreshments & Networking

In-Silico Tools for Vaccine Design

14.45
Structural Bioinformatics Methods for Immunogen Conformational Stabilization

  • Gwo-Yu Chuang Staff Scientist and Co-head, Structural Bioinformatics Core Section, Vaccine Research Center, NIAID/NIH

15.15
Applying Computational Tools to Structure Based Vaccine Design

  • Jerome Baudry Pei-Ling Chan Eminent Scholar & Professor, University Of Alabama In Huntsville

15.45
Chair’s Closing Remarks