13-15 November 2018

Woburn, Boston, MA

Day One
Wednesday 14th November 2018

Day Two
Thursday 15th November 2018

07.30
Registration & Refreshments

08.20
Chair’s Opening Remarks

08.30
From Conformation to Population & Back Again

Computational Tools for Accelerating Antibody & Target Selection

09.00
Applications of Current Computational Tools for Antibody Development

  • Bojana Popovic Principal Scientist - Antibody Discovery and Protein Engineering, MedImmune Protein Engineering, , MedImmune

09.30
Integrating Structural Data with the Human Interactome to Support Target Discovery & Characterization

10.00
Developability Risk Assessment for Novel Biologics Selection in Lead Generation Process

10.30
Speed Networking

11.00
Morning Refreshment Break

Predicting Protein Liabilities and Improving of Developability

11.30
Deep Sequencing Combined with In-Silico Modelling to Advance Biotherapeutic Discovery

12.00
Advances in Machine Learning Techniques Using Protein-Specific Descriptors for Liability Prediction Modeling

12.30
Lunch & Networking

13.30
Designing Aggregation Resistance by Mapping Key Inter-Protein Amino Acid Pairings

  • Chris Roberts Professor of Chemical and Biomolecular Engineering, University of Delaware

14.00
Molecular Dynamics for Antibody Developability Prediction

Computer-Aided Prediction of Structure and Design of Function

14.30
Afternoon Refreshments & Networking

15.30
Antibody Structure Prediction, Docking & Design

  • Jeffrey Grey Professor Chemical & Biomolecular Engineering, Johns Hopkins University School of Medicine

16.00
ADAPTing CDR H3: Re-engineering H3 Loops Using a Germline Sequence Library

  • Enrico O. Purisima Molecular Modeling Team Leader, National Research Council Canada, Human Health Therapeutics Research Centre

16.30
RosettaAntibodyDesign (RAbD): A General Framework for Computational Antibody Design

17.00
End of Conference Day One

Drinks Reception & Poster Session